A.V. Sanin, A.N. Narovlyansky, A.V. Pronin, T.N.Kozhevnikova, V.Yu.Sanina, Anna V.Izmesteva, Anastasiya V.Izmesteva V.V. Annikov, L.V.Annikova,

Here we studied the effectiveness of Phosprenyl in the complex therapy for diagnosed pancreatitis in dogs. In total, the study included 20 dogs of different sex, age and breed groups, divided into 2 groups of 10 animals each according to the principle of analogues. Of these, 5 dogs in each group were diagnosed with acute pancreatitis and 5 - with chronic. The results showed that at 5 days of therapy in Phosprenyl-treated group disappearance of clinical signs of pancreatitis in dogs with chronic disease was observed as well as weakening of the disease signs in animals with the acute form of pancreatitis. In the blood sera of patients with chronic pancreatitis after 5 days of therapy a sharp decline in the level of pancreatic lipase, cholesterol, α-amylase was observed, more pronounced in the Phosprenyl-treated group.

By the end of treatment (14 days) in the sera of the control animals increased activity of transferases, cholesterol and triglycerides was still observed. In contrast, in the sera of Phosprenyl-treated dogs these figures were already in the normal range. The level of pancreatic lipase by day 14 was also dropped to normal in Phosprenyl-treated patients, but still remained elevated in the control group.

We conclude that inclusion of Phosprenyl in the therapy of pancreatitis in dogs allows to reduce terms of recovery and prevent relapse of the disease.

Keywords: dogs, phosprenyl, pancreatitis, treatment, prophylaxis, pancreatic protection, pancreatic lipase, α-amilase, liver enzymes, transferases, coprogram

Veterinaria Kubani №2, 2017